The Premium core has out-of-the-box support of TUN device. Being a Network layer device, it can be used to handle TCP, UDP, ICMP traffic. It has been extensively tested and used in production environments - you can even play competitive games with it.
One of the biggest advantage of using Clash TUN is the built-in support of the automagic management of the route table, routing rules and nftable. You can enable it with the options tun.auto-route and tun.auto-redir. It's a drop-in replacement of the ancient configuration option redir-port (TCP) for the sake of easier configuration and better stability.